Ibutamoren, MK677 Review: Effects, Risks, and Legal Alternative

Ibutamoren (also known as Nutrobal, Ibutamoren Mesylate or MK677) is an orally active muscle-building prohormone used to increase growth hormone (GH) levels.

Ibutamoren, although marketed as belonging to the SARM family, is actually a non-peptide stimulant of GH secretion.

Despite the fact that it is illegal to sell this steroid for human consumption, it is available on the Internet.

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What is Ibutamoren, MK677 used for?

Ibutamoren is most commonly used by bodybuilders looking to gain muscle mass and build muscle in a short amount of time.

The compound provides increased protein synthesis and nitrogen retention in muscles. The user becomes fuller and more pumped up and is required to recover faster from workouts.

Elderly patients with hip fractures have also been tested on Ibutamoren to prevent muscle wasting due to injury or illness.

The connection has helped reduce the number of falls that these patients suffer. Steroid use has also been shown to reduce protein loss and muscle loss in people with unhealthy diets or lifestyles.

In addition, MK677 helps seniors produce stronger bones through increased mineral density and faster bone turnover.

This effect was confirmed in a study with postmenopausal women, in which this compound was effective in preventing osteoporosis.

Some people have also used this compound for its nootropic effects, that is, as a cognitive enhancer.

Ibutamoren can do this indirectly, by stimulating the ghrelin receptor, which increases REM sleep and insulin-like growth factor (IGF-1).

It can be effective for improving memory and learning. However, empirical evidence has yet to support this claim.

Finally, Ibutamoren, MK677, has been used for wound healing and tissue regeneration, another growth hormone boosting effect. Science, however, has yet to determine if the compound can deliver for this purpose.

What is known about this particular tutorial is still mostly anecdotal.

What are the consequences of the cycle “Ibutamoren, MK677”?

As stated, Ibutamoren, MK677, allows athletes to build muscle quickly.

In a single cycle (usually 4-5 weeks), users can gain 10 to 15 pounds of lean body mass.

In addition, the compound will redirect excess calories to muscle mass. This would have been impossible to achieve naturally.

How does this affect your body?

Ibutamoren, MK677, claims to be able to “transform” his body in a number of ways. Once swallowed, the compound instructs the pituitary gland to secrete more GH.

When GH enters the bloodstream, it stimulates the secretion of IGF-1 in the liver.

Although not yet proven in humans, it is believed that additional amounts of IGF-1 can cause cellular hyperplasia, which is the splitting of myofibrils in two to create new muscle fibers.

This results in the production of 6-8 new pounds of muscle mass, which can be much larger when combined with an appropriate diet and lifting cycle.


While further research is needed to fully understand the potential of ibutamoren, MK677, its most important characteristic is undoubtedly its increased production of growth hormones.

This has some advantages. Namely the following:

  • Increases protein synthesis and nitrogen retention in muscles. The result is more muscle mass and faster recovery after exercise. This powerful cycle is amplified: after training and generating body weight, the period after which the athlete can return to it is significantly reduced.
  • Something that always worries bodybuilders is the end of a substance cycle, because the effects achieved with continued consumption seem to have been lost. Ibutamoren, on the other hand, allows athletes to stay pumped even while dieting: during minimal periods of calorie intake, MK677 will force the body to burn fat instead of glycogen and muscle.
  • Obviously, at a certain age, the human body stops naturally producing growth hormone. Rumor evidence from Ibutamoren, MK677 states that because it boosts GH secretion to unprecedented levels, it provides anti-aging benefits such as smoother, healthier skin and hair, and tighter bones. Users report that they feel better overall.
  • Stimulation of the ghrelin receptor increases the duration of REM sleep, resulting in better lucid and unclear sleep and an overall feeling of good rest. Just what any athlete needs: a good, invigorating sleep to maintain a routine and not overload it.

Side effects

Ibutamoren, MK677 proponents claim that this substance does not cause any side effects at all, with little or no, but the truth is that there hasn’t been an exhaustive clinical study to support this claim.

In addition, one study was discontinued due to serious side effects. The most commonly reported side effects include the following:

  • People complain of muscle pain and numbness in their arms. This pain makes it difficult for athletes to exercise regularly.
  • People experience weight gain other than increased lean body mass, especially when meals are not followed by a rigorous diet. Ibutamoren, MK 677, increases appetite so users can increase their calorie intake beyond what they can burn.
  • Consumption of ibutamor, MK677, results in fluid retention, which in turn can lead to mild edema (swelling) of the lower extremities.
  • In the long term, the use of this product can lead to insulin resistance, a pathological condition directly related to high blood sugar and possibly type 2 diabetes.
  • Ibutamoren, MK677, may also raise blood pressure and cause heart failure, although the study that produced these results included older patients who were already suffering from these conditions.
  • Like any growth hormone-boosting product, this compound is strictly prohibited for cancer patients as it promotes the growth of tumors.
  • Side effects are the same in women. Unlike products that contain male sex hormones, MK677 is not androgenic, which means it will not virilize female athletes.

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